Bioengineering and specifically tissue engineering offers a new way to approach personalized regenerative medicine. It is now a common practice to use cells and therapies to help the body heal itself. This already happens with blood transfusions and bone marrow transplants.
These protocols have opened the door to over 2000 clinical trials in cell therapies. They include stem cells for ischemic heart areas, neural precursor cells of Parkinson's disease, and oligodendrocytes that are derived from embryonic stem cells. This article will focus on various approaches used in regenerative medicine these days.
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Regenerative medicine anticipates several things:
-A rising impact of cell-based therapies in clinical medicine
-Methods that make it easy to regenerate skin, bone, cartilage, bladder, and trachea from bone marrow stem cells, and also the regeneration of blood vessels and heart valves
-The restoration of function in complex tissues like the spinal cord
-Going after the goal of regenerating more complex tissues and neo-organs
Finding the best way to transfer these cells is key to your success. Cell-based therapy can be used to treat osteoarthritis of the knee. This is because the cartilage damage and subchondral bone fractures produce less fibrocartilage repair than articular cartilage's mechanical properties.
A majority of patients suffer from acute degenerative joint disease. Over 250,000 knee replacements are performed annually. A suspension of autologous cultured cartilage cells will not work in this instance. The cells are prone to form fibrocartilage and lose their round shape.
Osteoarthritis of the knee can be treated by embedding the chondrocytes into the cartilaginous matrix. This will allow the cartilage to wear away as well. The chondrocytes can be protected with gels to preserve their round shape. The mesh must be strong enough to support the cells and flexible enough to allow for water and nutrients to flow freely.